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Numb or Cold Fingers and Toes?

Raynaud's disease causes smaller arteries to narrow and fingers and toes to feel numb and cold in response to cold temperatures or stress. It can also affect other areas, such as the nose, lips, ears and even nipples, which turn from white to blue and as the blood returns, they flush red. Raynaud's disease affects 5 - 10 % of adults, but only 1 in 10 seek treatment. Females are about nine times more likely to be affected than males. Secondary Raynaud's, also called Raynaud's phenomenon, is caused by an underlying problem such as autoimmune disease. Although secondary Raynaud's is less common, it tends to be more serious, and signs and symptoms usually appear around age 40. A small study found that a compounded cream may improve blood flow. By prescription, our compounding pharmacy can prepare medications as topical creams and gels that are not commercially available.


J Am Acad Dermatol. 2018 Jan;78(1):189-190.

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